Detailed information
COMPOSITION :
Each suppository contains: 12.5mg didofenac sodium.
Each suppository contains: 25mg didofenac sodium.
Each suppository contains: 100 mg didofenac sodium.
Each Ent. ctd. tablets contains: 50 mg / 25mg didofenac sodium.
PROPERTIES:
DICLOBAR, a phenylacetic acid derivative is a Non-steroidal anti-inflammatory agent, it has anti-inflammatory, analgesic, and antipyretic properties, and it is an inhibitor of cydoxygenase, which results in the inhibition of the prostaglandin synthesis.
INDICATIONS:
* DICLOBAR is used for the relief of pain and inflammatory disorders such as: osteoa-rthritis, rheumatoid arthritis, ankylosing spondylitis, pen-articular disorders such as:
tendinitis, sprains and strains and other pain conditions such as: renal colic, acute gout, dysmenorrhoea and post operative pain.
* DICLOBAR is used tor temporary reduction of fever. CONTRAINDICATIONS:
* Active peptic ulceration.
* Hypersensitivity to aspirin or to other Non-steroidal anti-inflammatory agents.
* Pregnancy.
SIDE EFFECTS:
nausea, vomiting, bleeding, ulceration ofgastrointestinal tract, skin rashes, headache, dizziness, bronchospasm, and local irritation and rarely renal damage.
PRECAUTIONS:
* DICLOBAR should be used with caution in patients with asthma, bleeding disorders and liver or renal failure.
* The concomitant use of more than one NSAID should be avoided because of the incr¬eased risk of adversed effects.
DRUG INTERACTIONS:
* DICLOBAR increases the plasma concentrations of digoxin
* DICLOBAR reduces the effects of diuretics.
* Care is required in those who are receiving cun-iarin anticoagulants because DICLOBAR'increases the effects.
DOSAGE AND ADMINISTRATION:
Children 1-12 years: 1 -3 mg per kg body weight daily in divided doses. Adults: Generaly 100 - 150mg daily in 2 - 3 doses. Note: Tablets of enteric coating should be swallowed as a whole without chewing.
PRESENTATION :
Boxes of 10 suppositories of 12.5mg.
Boxes of 10,6 suppositories of 25mg.
Boxes of 10,6 suppositories of 100mg.
Boxes of 30 Ent ctd. tablets of 50mg7 25mg.
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